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Congress Abstracts
SASOP Biological Psychiatry Congress 2013 Abstracts
Submitted: 23 July 2013 | Published: 30 August 2013
About the author(s)
E Allers, Psychiatrist in Private Practice, South AfricaE Allers, Psychiatrist in Private Practice
O A Betancourt, Department of Psychiatry, Faculty of Health Sciences, Walter Sisulu University, Mthatha, South Africa
J Benson-Martin, University of Cape Town and Valkenberg Hospital, Cape Town, South Africa
P Buckley, Medical College of Georgia, Georgia Regents University, Augusta, Georgia, USA
P Buckley, Medical College of Georgia, Georgia Regents University, Augusta, Georgia, USA
I Chetty, Psychiatrist in Private Practice
B Chiliza, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
P Cilliers, Psychiatrist in Private Practice
H Clark, Child, Adolescent and Family Unit, Chris Hani Baragwanath Hospital, Soweto, Johannesburg, South Africa
P Cowen, Department of Psychiatry, University of Oxford, Oxford, UK
L Dannatt, Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
A K Domingo, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
K Domschke, Department of Psychiatry, University of Wuerzburg, Germany
S du Plessis, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
P Haddad, Consultant Psychiatrist, Greater Manchester West Mental Health NHS Foundation Trust, UK; Honorary Reader, Neuroscience and Psychiatry Unit, University of Manchester, UK
S Hemmings, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
D C Henderson, Department of Psychiatry, University of Montreal, Quebec, Canada
V Hitzeroth, Psychiatrist in Private Practice
B Janse van Rensburg, Department of Psychiatry, University of the Witwatersrand, Johannesburg, South Africa
S Janse van Rensburg, Department of Chemical Pathology, Stellenbosch University, Cape Town, South Africa; National Health Laboratory Service, Cape Town, South Africa
G Jordaan, Department of Psychiatry,Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa
L Kramer, Private Practice
A Lachman,
B Latecki, Philosophy Department, University of Zululand, Empangeni, South Africa; Empangeni Garden Clinic, Empangeni, South Africa
P Macqueen, Viva Youth College, Kyalami, South Africa; Viva Youth Centre SDN Bhd for outpatients, Malaysia
N McGregor, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
A Moodley, Grey’s Hospital, Pietermaritzburg, South Africa
Z M Moosa, Discipline of Human Physiology, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa
L Mubaiwa, Department of Paediatric Neurology, University of KwaZulu-Natal, Durban, South Africa
M Nagdee, Fort England Hospital, Department of Psychiatry, Walter Sisulu University, Grahamstown, South Africa
C Nemeroff, Department of Psychiatry and Behavioral Sciences, Leonard M Miller School of Medicine, University of Miami, Miami, Florida, USA
G Nortje, South African Research Chair in PTSD, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
A Ojagbemi, College of Medicine, University of Ibadan, Nigeria
E Peter, Psychiatrist in Private Practice
L Phahladira, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
W Pienaar, Department of Psychiatry, Faculty of Medicine and Health Sciences, Tygerberg Campus, Stellenbosch University, Cape Town, South Africa
S Ramlall, Department of Psychiatry, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa
S Rataemane, Medical University of South Africa, University of Limpopo, Turfloop, South Africa
A Roos, Medical Research Council Unit on Anxiety & Stress Disorders, Stellenbosch University, Cape Town, South Africa
D Rosenstein, South African Research Chairs Initiative in Post-Traumatic Stress Disorder, Department of Psychiatry, Faculty of Health Sciences, Tygerberg Campus, Stellenbosch University, Cape Town, South Africa
J Roux, Psychiatrist in Private Practice, SIG Cellular and Molecular Psychiatry
C Schumann, Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
M Solms, Department of Neurology, Groote Schuur Hospital, Cape Town, South Africa
G Spies, South African Research Chairs Initiative (SARChI), PTSD program, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
U Subramaney, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
S Suliman, Medical Research Council Anxiety Disorders Unit, Department of Psychiatry, Faculty of Medicine and Health Sciences, University of Stellenbosch, Cape Town, South Africa
S Suomi, Laboratory of Comparative Ethology, NICHD, NIH, Bethesda, Maryland, USA
C Szabo, Department of Psychiatry, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
H Uys, East London Mental Health Unit, Cecilia Makiwane Hospital, East London, South Africa
J van Tonder, Department of Pharmacology, School of Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa
J Zohar, Division of Psychiatry, Chaim Sheba Medical Center, Tel Hashomer, Israel
S Bakelaar, South African Research Chairs Initiative in Post-Traumatic Stress Disorder, Department of Psychiatry, Faculty of Health Sciences, Tygerberg Campus, Stellenbosch University, Cape Town, South Africa
E Breet, Medical Research Council Unit on Anxiety and Stress Disorders, Department of Psychiatry, Stellenbosch University, South Africa
A Bronkhorst, Department of Psychiatry Port Elizabeth Hospital Complex, Port Elizabeth, South Africa
W Davis, Department of Chemical Pathology, Stellenbosch University, Cape Town;National Health Laboratory Service, Cape Town, South Africa
D de Klerk, Department of Chemical Pathology, Stellenbosch University, Cape Town;National Health Laboratory Service, Cape Town, South Africa
D Delport, Department of Pathology, Faculty of Medicine and Health Sciences, University of Stellenbosch, Cape Town, South Africa
B Drögemöller, Department of Genetics, Stellenbosch University, Cape Town, South Africa
E du Toit, Sophia Maternal Mental Health Clinic, Panorama Psychiatric Clinic, Cape Town, South Africa
J P Fouche, Department of Human Biology, University of Cape Town, Cape Town; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town; Department of Psychiatry, University of Stellenbosch, Cape Town, South Africa
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List of abstracts and authors:
1. Bipolar disorder not otherwise specified -overdiagnosed or underdiagnosed?
E Allers
2. The prognosis of major depression untreated and treated: Does the data reflect the true picture of the prognosis of this very common disorder?
E Allers
3. Can we prolong our patients' life expectancy? Providing a better quality of life for patients with severe mental illness
O A Betencourt
4. The scope of ECT practice in South Africa
J Benson-Martin, P Milligan
5. Biomarkers for schizophrenia: Can we evolve like cancer therapeutics?
P Buckley
6. Relapse in schizophrenis: Major challenges in prediction and prevention
P Buckley
7. Informed consent in biological treatments: The right to know the duty to inform
I Chetty
8. Effectiveness of a long-acting injectable antipsychotic plus an assertive monitoring programme in first-episode schizophrenia
B Chiliza, L Asmal, O Esan, A Ojagbemi, O Gureje, R Emsley
9. Name, shame, fame
P Cilliers
10. Can we manage the increasing incidence of violent raging children? We have to!
H Clark
11. Serotonin, depression and antidepressant action
P Cowen
12. Prevalence and correlates of comorbid psychiatris illness in patients with heroin use disorder admitted to Stikland Opioid Detoxification Unit
L Dannatt, K J Cloete, M Kidd, L Weich
13. Investigating the association between diabetes mellitus, depression and psychological distress in a cohort of South African teachers
A K Domingo, S Seedat, T M Esterhuizen, C Laurence, J Volmink, L Asmal
14. Neuropeptide S -emerging evidence for a role in anxiety
K Domschke
15. Pathogenetics of anxiety
K Domschke
16. The effects of HIV on the fronto-striatal system
S du Plessis, M Vink, J Joska, E Koutsilieri, C Scheller, B Spottiswoode, D Stein, R Emsley
17. Effects of acute antipsychotic treatment on brain morphology in schizophrenia
R Emsley, L Asmal, B Chiliza, S du Plessis, J Carr, A Goosen, M Kidd, M Vink, R Kahn
18. Development of a genetic database resource for monitoring of breast cancer patients at risk of physical and psychological complications
K Grant, F J Cronje, K Botha, J P Apffelstaedt, M J Kotze
19. Unipolar mania reconsidered: Evidence from a South African study
C Grobler
20. Antipsychotic-induced movement disorders: Occurence and management
P Haddad
21. The place of observational studies in assessing the effectiveness of long-acting injectable antipsychotics
P Haddad
22. Molecular mechanisms of d-cycloserine in fear extinction: Insights from RNS sequencing
S Hemmings, S Malan-Muller, L Fairbairn, M Jalali, E J Oakeley, J Gamieldien, M Kidd, S Seedat
23. Schizophrenia: The role of inflammation
DC Henderson
24. Addictions: Emergent trends and innovations
V Hitzeroth
25. The socio-cultural-religious context of biological psychiatric practice
B Janse van Rensburg
26. Biochemical markers for identifying risk factors for disability progression in multiple sclerosis
S Janse van Rensburg, M J Kotze, F J Cronje, W Davis, K Moremi, M Jalali Sefid Dashti, J Gamieldien, D Geiger, M Rensburg, R van Toorn, M J de Klerk, G M Hon, T Matsha, S Hassan, R T Erasmus
27. Alcohol-induced psychotic disorder: Brain perfusion and psychopathology - before and after antipsychotic treatment
G Jordaan, J M Warwick, D G Nel, R Hewlett, R Emsley
28.'Pump and dump': Harm reduction strategies for breastfeeding while using substances
L Kramer
29. Adolescent neuropsychiatry - an emerging field in South African adolescent psychiatric services
A Lachman
30. Recovery versus remission, or what it means to be healthy for a psychiatric patient?
B Latecki
31. Holistic methods utilised to normalise behaviours in youth diagnosed with neuro-biochemical disorders
P Macqueen
32. Candidate genes and novel polymorphisms for anxiety disorder in a South African cohort
N McGregor, J Dimatelis, S M J Hemmings, C J Kinnear, D Stein, V Russel, C Lochner
33. Higher visual functioning
A Moodley
34. The effects of prenatal methylmercury exposure on trace element and antioxidant levels in rat offspring following 6-hydroxydopamine-induced neuronal insult
Z M Moosa, W M U Daniels, M V Mabandla
35. Paediatric neuropsychiatric movement disorders
L Mubaiwa
36. The South African national female offenders study
M Nagdee, L Artz, C de Clercq, P de Wet, H Erlacher, S Kaliski, C Kotze, L Kowalski, J Naidoo, S Naidoo, J Pretorius, M Roffey, F Sokudela, U Subramaney
37. Neurobiological consequences of child abuse
C Nemeroff
38. What do Stellenbosch Unviversity medical students think about psychiatry - and why should we care?
G Nortje, S Suliman, K Seed, G Lydall, S Seedat
39. Neurological soft skins in Nigerian Africans with first episode schizophrenia: Factor structure and clinical correlates
A Ojagbemi, O Esan, O Gureje, R Emsley
40. Should psychiatric patients know their MTHFR status?
E Peter
41. Clinical and functional outcome of treatment refractory first-episode schizophrenia
L Phahladira, R Emsley, L Asmal, B Chiliza
42. Bioethics by case discussion
W Pienaar
43. Reviewing our social contract pertaining to psychiatric research in children, research in developing countries and distributive justice in pharmacy
W Pienaar
44. The performance of the MMSE in a heterogenous elderly South African population
S Ramlall, J Chipps, A I Bhigjee, B J Pillay
45. Biological basis addiction (alocohol and drug addiction)
S Rataemane
46. Volumetric brain changes in prenatal methamphetamine-exposed children compared with healthy unexposed controls
A Roos, K Donald, G Jones, D J Stein
47. Single voxel proton magnetic resonance spectroscopy of the amygdala in social anxiety disorder in the context of early developmental trauma
D Rosenstein, A Hess, S Seedat, E Meintjies
48. Discussion of HDAC inhibitors, with specific reference to supliride and its use during breastfeeding
J Roux
49. Prevalence and clinical correlates of police contact prior to a first diagnosis of schizophrenia
C Schumann, L Asmal, K Cloete, B Chiliza, R Emsley
50. Are dreams meaningless?
M Solms
51. The conscious id
M Solms
52. Depression and resilience in HIV-infected women with early life stress: Does trauma play a mediating role?
G Spies, S Seedat
53. State of affairs analysis for forensic psychiatry in SA
U Subramaney
54. Escitalopram in the prevention of post-traumatic stress disorder: A pilot randomised controlled trial
S Suliman, S Seedat, J Pingo, T Sutherland, J Zohar, D J Stein
55. Epigenetic consequences of adverse early social experiences in primates
S Suomi
56. Risk, resilience, and gene x environment interactions in primates
S Suomi
57. Biological aspects of anorexia nervosa
C Szabo
58. Agents used and profiles of non-fatal suicidal behaviour in East London
H Uys
59. The contributions of G-protein coupled receptor signalling to opioid dependence
J van Tonder
60. Emerging trend and innovation in PTSD and OCD
J Zohar
61. Making the SASOP treatment guidelines operational
E Allers
Poster Presentations
62. Neuropsychological deficits in social anxiety disorder in the context of early developmental trauma
S Bakelaar, D Rosenstein, S Seedat
63.Social anxiety disorder in patients with or without early childhood trauma: Relationship to behavioral inhibition and activation and quality of life
S Bakelaar, C Bruijnen, A Sambeth, S Seedat
64. Exploring altered affective processing in obssessive compulsive disorder symptom subtypes
E Breet, J Ipser, D Stein, C Lochner
65. To investigate the bias toward recognising the facial expression of disgust in obsessive compulsive disorder as well as the effect of escitalopram
E Breet, J Ipser, D Stein, C Lochner
66. A fatal-case of nevirapine-induced Stevens-Johnson's syndrome in HIV mania
A Bronkhorst, Z Zingela, W M Qwesha, B P Magigaba
67. Association of the COMT G472A (met/met) genotype with lower disability in people diagnosed with multiple sclerosis
W Davis, S J van Rensburg, L Fisher, F J Cronje, D Geiger, M J Kotze
68. Homocycsteine levels are associated with the fat mass and obesity associated gene FTO(intron 1 T>A) polymorphism in MS patients
W Davis, S J Van Rensburg, M J Kotze, L Fisher, M Jalali, F J Cronje, K Moremi, J Gamieldien, D Geiger, M Rensburg, R van Toorn, M J de Klerk, G M Hon, T Matsha, S Hassan, R T Erasmus
69. Analysis of the COMT 472 G>A (rs4680) polymorphism in relation to environmental influences as contributing factors in patients with schizophrenia
D de Klerk, S J van Rensburg, R A Emsley, D Geiger, M Rensburg, R T Erasmus, M J Kotze
70. Dietary folate intake, homocysteine levels and MTHFR mutation detection in South African patients with depression: Test development for clinical application
D Delport, N vand der Merwe, R Schoeman, M J Kotze
71. The use ofexome sequencing for antipsychotic pharmacogenomic applications in South African schizophrenia patients
B Drogmoller, D Niehaus, G Wright, B Chiliza, L Asmal, R Emsley, L Warnich
72. The effects of HIV on the ventral-striatal reward system
S du Plessis, M Vink, J Joska, E Koutsilieri, C Scheller, B Spottiswoode, D Stein, R Emsley
73. Xenomelia relates to asymmetrical insular activity: A case study of fMRI
S du Plessis, M Vink, L Asmal
74. Maternal mental helath: A prospective naturalistic study of the outcome of pregancy in women with major psychiatric disorders in an African country
E du Toit, L Koen, D Niehaus, B Vythilingum, E Jordaan, J Leppanen
75. Prefrontal cortical thinning and subcortical volume decrease in HIV-positive children with encephalopathy
J P Fouche, B Spottiswoode, K Donald, D Stein, J Hoare
76. H-magnetic resonance spectroscopy metabolites in schizophrenia
F Howells, J Hsieh, H Temmingh, D J Stein
77. Hypothesis for the development of persistent methamphetamine-induced psychosis
J Hsieh, D J Stein, F M Howells
78. Culture, religion, spirituality and psychiatric practice: The SASOP Spirituality and Psychiatry Special Interest Group Action Plan for 2012-2014
B Janse van Rensburg
79. Cocaine reduces the efficiency of dopamine uptake in a rodent model of attention-deficit/hyperactivity disorder: An in vivo electrochemical study
L Kellaway, J S Womersley, D J Stein, G A Gerhardt, V A Russell
80. Kleine-Levin syndrome: Case in an adolescent psychiatric unit
A Lachman
81. Increased inflammatory stress specific clinical, lifestyle and therapeutic variables in patients receiving treatment for stress, anxiety or depressive symptoms
H Luckhoff, M Kotze, S Janse van Rensburg, D Geiger
82. Catatonia: An eight-case series report
M Mabenge, Z Zingela, S van Wyk
83. Relationship between anxiety sensitivity and childhood trauma in a random sample of adolescents from secondary schools in Cape Town
L Martin, M Viljoen, S Seedat
84. 'Making ethics real'. An overview of an ethics course presented by Fraser Health Ethics Services, BC, Canada
JJ McCallaghan
85. Clozapine discontinuation rates in a public healthcare setting
M Moolman, W Esterhuysen, R Joubert, J C Lamprecht, M S Lubbe
86. Retrospective review of clozapine monitoring in a publica sector psychiatric hospital and associated clinics
M Moolman, W Esterhuysen, R Joubert, J C Lamprecht, M S Lubbe
87. Association of an iron-related TMPRSS6 genetic variant c.2007 C>7 (rs855791) with functional iron deficiency and its effect on multiple sclerosis risk in the South African population
K Moremi, S J van Rensburg, L R Fisher, W Davis, F J Cronje, M Jalali Sefid Dashti, J Gamieldien, D Geiger, M Rensburg, R van Toorn, M J de Klerk, G M Hon, T Matsha, S Hassan, R T Erasmus, M Kidd, M J Kotze
88. Identifying molecular mechanisms of apormophine-induced addictive behaviours
Z Ndlazi, W Daniels, M Mabandla
89. Effects of lifestyle factors and biochemistry on the major neck blood vessels in patients with mutiple sclerosis
M Nelson, S J van Rensburg, M J Kotze, F Isaacs, S Hassan
90. Nicotine protects against dopamine neurodegenration and improves motor deficits in a Parkinsonian rat model
N Ngema, P Ngema, M Mabandla, W Daniels
91. Cognition: Probing anatomical substrates
H Nowbath
92. Chronic exposure to light reverses the effects of maternal separation on the rat prefrontal cortex
V Russel, J Dimatelis
93. Evaluating a new drug to combat Alzheimer's disease
S Sibiya, W M U Daniels, M V Mabandla
94. Structural brain changes in HIV-infected women with and without childhood trauma
G Spies, F Ahmed, C Fennema-Notestine, S Archibald, S Seedat
95. Nicotine-stimulated release of hippocampal norepinephrine is reduced in an animal model of attention-deficit/ hyperactivity disorder: the spontaneously hypertensive rat
T Sterley
96. Brain-derive neurotrophic factor (BDNF) protein levels in anxiety disorders: Systematic review and meta-regression analysis
S Suliman, S M J Hemmings, S Seedat
97. A 12-month retrospective audit of the demographic and clinical profile of mental healthcare users admitted to a district level hospital in the Western Cape, South Africa
E Thomas, K J Cloete, M Kidd, H Lategan
98. Magnesium recurarization: A comparison between reversal of neuromuscular block with sugammadex v. neostigmine/ glycopyrrolate in an in vivo rat model
M van den Berg, M F M James, L A Kellaway
99. Identification of breast cancer patients at increased risk of 'chemobrain': Case study and review of the literature
N van der Merwe, R Pienaar, S J van Rensburg, J Bezuidenhout, M J Kotze
100. The protective role of HAART and NAZA in HIV Tat protein-induced hippocampal cell death
S Zulu, W M U Daniels, M V Mabandla
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