Original Research

Anxiety and depressive features in chronic disease patients in Cambodia, Myanmar and Vietnam

Karl Peltzer, Supa Pengpid
South African Journal of Psychiatry | Vol 22, No 1 | a940 | DOI: https://doi.org/10.4102/sajpsychiatry.v22i1.940 | © 2016 Karl Peltzer, Supa Pengpid | This work is licensed under CC Attribution 4.0
Submitted: 04 January 2016 | Published: 28 July 2016

About the author(s)

Karl Peltzer, ASEAN Institute for Health Development, Madidol University, Thailand, Department of Research Innovation and Development, University of Limpopo, South Africa and HIV/AIDS/STIs and TB (HAST), Human Sciences Research Council, Pretoria, South Africa
Supa Pengpid, ASEAN Institute for Health Development, Madidol University, Thailand and Department of Research Innovation and Development, University of Limpopo, South Africa

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Objective: The aim of this study was to estimate the prevalence and relationship of anxiety and depressive features among patients diagnosed with a variety of chronic diseases in three Southeast Asian countries (Cambodia, Myanmar and Vietnam).
Methods: A cross-sectional survey was conducted in 2014 among 4803 adult patients with chronic diseases who were recruited cross-sectionally from health facilities. Anxiety and depression were assessed with the Hospital Anxiety and Depression Scale.
Results: Overall, 17.0% of patients screened positive for anxiety disorder and 39.1% for depressive disorder. Patients with cancer (47.8%) had the highest rate of anxiety features, and those with chronic obstructive pulmonary disease (COPD) (62.1%), kidney disease (55.5%), Parkinson’s disease (53.7%) and cardiovascular disorders (CVDs) (52.6%) the highest prevalence of depressive features. Stomach and intestinal diseases, CVDs, migraine or frequent
headaches and kidney disease were positively associated with anxiety and depression after adjusting for sociodemographics and illness duration. In addition, cancer and Parkinson’s disease were positively associated with anxiety, and arthritis, diabetes, and COPD were positively associated with depression. In multivariate logistic regression, having two or more chronic conditions and poor quality of life was associated with anxiety and depression.
Conclusion: Considering the high rate of anxiety and depression among these patients with chronic disease, more efforts should directed to on the psychosocial management of these patients.


Anxiety; depression; chronic diseases; comorbidity; Cambodia; Myanmar; Vietnam


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