Original Research

Relationship between substance abuse and first-episode psychosis - a South African perspective

Sandra Brink, Piet Oosthuizen, Robin Emsley, Irene Mbanga, Natasha Keyter
South African Journal of Psychiatry | Vol 9, No 1 | a129 | DOI: https://doi.org/10.4102/sajpsychiatry.v9i1.129 | © 2003 Sandra Brink, Piet Oosthuizen, Robin Emsley, Irene Mbanga, Natasha Keyter | This work is licensed under CC Attribution 4.0
Submitted: 11 August 2008 | Published: 01 July 2003

About the author(s)

Sandra Brink, Department of Psychiatry , University of Stellenbosch, Tyger berg, Western Cape, South Africa
Piet Oosthuizen, Department of Psychiatry , University of Stellenbosch, Tyger berg, Western Cape
Robin Emsley, Department of Psychiatry , University of Stellenbosch, Tyger berg, Western Cape
Irene Mbanga, Department of Psychiatry , University of Stellenbosch, Tyger berg, Western Cape
Natasha Keyter, Department of Psychiatry , University of Stellenbosch, Tyger berg, Western Cape

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Abstract

Background. Co-morbidity between substance abuse and psy- chotic disorders is high. Few studies have examined therelationship between first-episode psychosis and substance abuse. Several questions emerge from this common relationship and many of them remain unanswered.

Objectives. To determine the effect of substance abuse on psychosis in terms of onset, duration, severity of symptoms, use of medication and outcome.

Method. Thirty - three subjects with first-episode psychosis, as well as primary caregivers, were interviewed re g a rding substance abuse and its relation to illness. Thirty-six control subjects were also interv i e w e d .

Results. Twenty-seven per cent of subjects abused substances in the 3 months before onset of illness, and 77.8% of the abusers w e re male. Subjects in the first-episode psychosis group were m o re likely to choose cannabis as their substance of abuse than c o n t rols. They also started abusing substances at a younger age than controls. Subjects with first-episode psychosis who abused substances presented at an earlier age than non-abusers. Substances affected symptoms at baseline presentation .

Conclusions. Substance abuse has a significant impact on first- onset psychosis as far as age of onset and symptom severity are c o n c e rned. Subjects with an underlying vulnerability to psychosis seem to start abusing substances at an earlier age than the general population. Males are more likely to abuse substances than females.


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Crossref Citations

1. Cannabis use and family history in adolescent first episode psychosis in Durban, South Africa
Saeeda Paruk, Jonathan K Burns, Rochelle Caplan
Journal of Child & Adolescent Mental Health  vol: 25  issue: 1  first page: 61  year: 2013  
doi: 10.2989/17280583.2013.767264