Congress Abstracts
Biological Psychiatry Congress 2015
Submitted: 16 September 2015 | Published: 01 August 2015
About the author(s)
H Temmingh, Department of Psychiatry and Mental Health, University of Cape Town, South AfricaD J Stein, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
F M Howells, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
U A Botha, Department of Psychiatry, University of Stellenbosch, Cape Town, South Africa
L Koen, Department of Psychiatry, University of Stellenbosch, Cape Town, South Africa
M Mazinu, Medical Research Council, Cape Town, South Africa
E Jordaan, Medical Research Council, Cape Town, South Africa
D J H Niehaus, Medical Research Council, Cape Town, South Africa
A Burger, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
S Brooks, Department of Psychiatry and Mental Health, University of Cape Town, South Africa, South Africa
D J Stein, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
F M Howells, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
A Burger, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
A Roos, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
M Kwiatkowski, Department of Psychology, University of Cape Town, South Africa
D J Stein, Department of Psychiatry and Mental Health, University of Cape Town
K A Donald, Division of Developmental Paediatrics, Department of Paediatrics and Child Health, Red Cross War Memorial Children’s Hospital, University of Cape Town
F M Howells, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
B Chiliza, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
L Asmal, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
R Emsley, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
H M Clark, Department of Child and Adolescent Psychiatry, Chris Hani Baragwanath Hospital, Soweto, Johannesburg, South Africa
Ilse du Plessis, Department of Psychiatry, University of Pretoria; Weskoppies Hospital, Pretoria, South Africa
Ilse du Plessis, Department of Psychiatry, University of Pretoria; Weskoppies Hospital, Pretoria, South Africa
S du Plessis, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
M Vink, Brain Center Rudolf Magnus, University of Utrecht, Utrecht, The Netherlands
J A Joska, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
E Koutsilieri, Institute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany
A Bagadia, Department of Radiology, Stellenbosch University, Cape Town, South Africa
D J Stein, Department of Psychiatry and Mental Health, University of Cape Town;Medical Research Council Unit on Anxiety and Stress Disorders, Cape Town, South Africa
R Emsley, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
R Emsley, Sarah Turoff Endowed Chair in Schizophrenia Research, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
M J Sian, Sarah Turoff Endowed Chair in Schizophrenia Research, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
S M J Hemmings, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
L I Martin, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
L van der Merwe, Department of Statistics, University of the Western Cape, Bellville, South Africa
R Benecke, Department of Biomedical Sciences, Stellenbosch University, Cape Town, South Africa
K Domschke, Department of Psychiatry, University of Würzburg, Würzburg, Germany
S Seedat, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
S Janse van Rensburg, Chemical Pathology, NHLS and Stellenbosch University, Cape Town, South Africa
R Van Toorn, Department of Paediatrics and Child Health, Tygerberg Children’s Hospital, Stellenbosch University, Cape Town, South Africa
J F Schoeman, Department of Paediatrics and Child Health, Tygerberg Children’s Hospital, Stellenbosch University, Cape Town, South Africa
A Peeters, Anatomical Pathology, NHLS and Stellenbosch University, Cape Town, South Africa
L R Fisher, Anatomical Pathology, NHLS and Stellenbosch University, Cape Town, South Africa
K Moremi, Chemical Pathology, NHLS and Stellenbosch University, Cape Town, South Africa
M J Kotze, Anatomical Pathology, NHLS and Stellenbosch University, Cape Town, South Africa
P Joubert, University of Pretoria, South Africa
G Lippi, Department of Psychiatry, University of Pretoria; Forensic Unit, Weskoppies Hospital, Pretoria, South Africa
C Lochner, MRC Unit on Anxiety and Stress Disorders; Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
L Taljaard, MRC Unit on Anxiety and Stress Disorders; Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
D J Stein, MRC Unit on Anxiety and Stress Disorders; Department of Psychiatry, Stellenbosch University, Cape Town, South Africa; Department of Psychiatry and Mental Health, University of Cape Town, South Africa
K-A Louw, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
N Phillips, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
J Ipser, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
J Hoare, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
S Malan-Muller, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
L Fairbairn, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
W M U Daniels, Department of Human Physiology, University of KwaZulu-Natal, Durban, South Africa
M J S Dashti, South African National Bioinformatics Institute, University of the Western Cape, Cape Town
E J Oakeley, Novartis Institutes for BioMedical Research, Biomarker Development - Human Genetics and Genomics, Genome Technologies, Basel, Switzerland
M Altorfer, Novartis Institutes for BioMedical Research, Biomarker Development - Human Genetics and Genomics, Genome Technologies, Basel, Switzerland
J Harvey, Centre for Statistical Consultation, Stellenbosch University, Stellenbosch, South Africa
S Seedat, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
J Gamieldien, South African National Bioinformatics Institute, University of the Western Cape, Cape Town
S M J Hemmings, Department of Psychiatry, Stellenbosch University, Cape Town; Division of Molecular Biology and Human Genetics, Stellenbosch University, Cape Town, South Africa
M L Maodi, Department of Psychiatry, Sefako Makgatho Health Sciences University, Pretoria, South Africa
S T Rataemande, Department of Psychiatry, Sefako Makgatho Health Sciences University, Pretoria, South Africa
T Kyaw, Department of Virology, Sefako Makgatho Health Sciences University, Pretoria, South Africa
N W McGregor, Department of Psychiatry and Department of Genetics, Stellenbosch University, Cape Town, South Africa
J Dimatelis, Department of Human Biology, University of Cape Town, South Africa
S M J Hemmings, Department of Psychiatry and Department of Genetics, Stellenbosch University, Cape Town, South Africa
C J Kinnear, Department of Molecular Biology and Human Genetics, Stellenbosch University, South Africa
D J Stein, MRC Unit on Anxiety and Stress Disorders, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
V Russel, MRC Unit on Anxiety and Stress Disorders, Department of Psychiatry and Mental Health, University of Cape Town, South Africa
G Nortje, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa
Full Text:
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List of Abstract Titles and authors:
1. Psychosis: A matter of mental effort?
M Borg, Y Y van der Zee, J H Hsieh, H Temmingh, D J Stein, F M Howells
2.In search of an affordable, effective post-discharge intervention: A randomised control trial assessing the influence of a telephone-based intervention on readmissions for patients with severe mental illness in a developing country
U A Botha, L Koen, M Mazinu, E Jordaan, D J H Niehaus
3. The effect of early abstinence from long-term methamphetamine use on brain metabolism using 1H-magnetic resonance spectro-scopy (1H-MRS)
A Burger, S Brooks, D J Stein, F M Howells
4. The effect of in utero exposure to methamphetamine on brain metabolism in childhood using 1H-magnetic resonance spectroscopy (1H-MRS)
A Burger, A Roos, M Kwiatkowski, D J Stein, K A Donald, F M Howells
5. A prospective study of clinical, biological and functional aspects of outcome in first-episode psychosis: The EONKCS Study
B Chiliza, L Asmal, R Emsley
6. Stimulants as cognitive enhancers - perceptions v. evidence in a very real world
H M Clark
7. Pharmacogenomics in antipsychotic drugs
Ilse du Plessis
8. Serotonin in anxiety disorders and beyond
Ilse du Plessis
9. HIV infection results in ventral-striatal reward system hypo-activation during cue processing
S du Plessis, M Vink, J A Joska, E Koutsilieri, A Bagadia, D J Stein, R Emsley
10. Disease progression in schizophrenia: Is the illness or the treatment to blame?
R Emsley, M J Sian
11. Serotonin transporter variants play a role in anxiety sensitivity in South African adolescents
S M J Hemmings, L I Martin, L van der Merwe, R Benecke, K Domschke, S Seedat
12. Iron deficiency in two children diagnosed with multiple sclerosis: Report on whole exom sequencing
S Janse van Rensburg, R van Toorn, J F Schoeman, A Peeters, L R Fisher, K Moremi, M J Kotze
13. Benzodiazepines: Practical pharmacokinetics
P Joubert
14. What to consider when prescribing psychotropic medications
G Lippi
15. Current prescribing practices for obsessive-compulsive disorder in South Africa: Controversies and consensus
C Lochner, L Taljaard, D J Stein
16. Correlates of emotional and behavioural problems in children with preinatally acquired HIV in Cape Town, South Africa
K-A Louw, N Phillips, JIpser, J Hoare
17. The role of non-coding RNAs in fear extinction
S Malan-Muller, L Fairbairn, W M U Daniels, M J S Dashti, E J Oakleley, M Altorfer, J Harvey, S Seedat, J Gamieldien, S M J Hemmings
18. An analysis of the management og HIV-mental illness comorbidity at the psychiatric unit of the Dr George Mukhari Academic Hospital
M L Maodi, S T Rataemane, T Kyaw
19. The identification of novel genes in anxiety disorders: A gene X environment correlation and interaction study
N W McGregor, J Dimatelis, S M J Hemmings, C J Kinnear, D J Stein, V Russel, C Lochner
20. Collaborations between conventional medicine and traditional healers: Obstacles and possibilities
G Nortje, S Seedat, O Gureje
21. Thought disorder and form perception: Relationships with symptoms and cognitive function in first-episode schizophrenia
M R Olivier, R Emsley
22. Investigating the functional significance of genome-wide variants associated with antipsychotic treatment response
E Ovenden, B Drogemoller, L van der Merwe, R Emsley, L Warnich
23. The moral and bioethical determinants of "futility" in psychiatry
W P Pienaar
24. Single voxel proton magnetic resonance spectroscopy (1H-MRS) and volumetry of the amylgdala in social anxiety disorder in the context of early developmental trauma
D Rosenstein, A T Hess, J Zwart, F Ahmed-Leitao, E Meintjies, S Seedat
25. Schizoaffective disorder in an acute psychiatric unit: Profile of users and agreement with Operational Criteria (OPCRIT)
R R Singh, U Subramaney
26. The right to privacy and confidentiality: The ethics of expert diagnosis in the public media and the Oscar Pistorius trial
C Smith
27. A birth cohort study in South Africa: A psychiatric perspective
D J Stein
28. 'Womb Raiders': Women referred for observation in terms of the Criminal Procedures Act (CPA) charged with fetal abduction and murder
U Subramaney
29. Psycho-pharmacology of sleep wake disorders: An update
R Sykes
30. Refugee post-settlement in South Africa: Role of adjustment challenges and family in mental health outcomes
L Thela, A Tomita, V Maharaj, M Mhlongo, K Jonathan
31. Dstinguishing ADHD symptoms in psychotic disorders: A new insight in the adult ADHD questionnaire
Y van der Zee, M Borg, J H Hsieh, H Temmingh, D J Stein, F M Howells
32. Oscar Pistorius ethical dilemmas in a trial by media: Does this include psychiatric evaluation by media?
M Vorster
33. Genetic investigation of apetite aggression in South African former young offenders: The involvement of serotonin transporter gene
K Xulu, J Somer, M Hinsberger, R Weierstall, T Elbert, S Seedat, S Hemmings
34. Effects of HIV and childhood trauma on brain morphemtry and neurocognitive function
G Spies, F Ahmed-Leitao, C Fennema-Notestine, M Cherner, S Seedat
35. Measuring intentional behaviour normative data of a newly developed motor task battery
S Bakelaar, J Blampain, S Seedat, J van Hoof, Y Delevoye-Turrel
36. Resilience in social anxiety disorder and post-traumatic stress disorder in the context of childhood trauma
M Bship, S Bakelaar, D Rosenstein, S Seedat
37. The ethical dilemma of seclusion practices in psychiatry
G Chiba, U Subramaney
38. Physical activity and neurological soft signs in patients with schizophrenia
O Esan, C Osunbote, I Oladele, S Fakunle, C Ehindero
39. A retrospective study of completed suicides in the Nelson Mandela Bay Metropolitan Area from 2008 to 2013 - preliminary results
C Grobler, J Strumpher, R Jacobs
40. Serotonin transporter variants play a role in anxiety sensitivity in South African adolescents
S M J Hemmings, L I Martin, L van der Merwe, R Benecke, K Domschke, S Seedat
41. Investigation of variants within antipsychotic candidate pharmacogenes associated with treatment outcome
F Higgins, B Drogmoller, G Wright, L van der Merwe, N McGregor, B Chiliza, L Asmal, L Koen, D Niehaus, R Emsley, L Warnich
42. Effects of diet, smoking and alcohol consumption on disability (EDSS) in people diagnosed with multiple sclerosis
S Janse van Rensburg, W Davis, D Geiger, F J Cronje, L Whati, M Kidd, M J Kotze
43. The clinical utility of neuroimaging in an acute adolescnet psychiatric inpatient population
Z Khan, A Lachman, J Harvey
44. Relationships between childhood trauma (CT) and premorbid adjustment (PA) in a highly traumatised sample of patients with first-episode schizophrenia (FES)
S Kilian, J Burns, S Seedat, L Asmal, B Chiliza, S du Plessis, R Olivier, R Emsley
45. Functional and cognitive outcomes using an mTOR inhibitor in an adolescent with TSC
A Lachman, C van der Merwe, P Boyes, P de Vries
46. Perceptions about adolescent body image and eating behaviour
K Laxton, A B R Janse van Rensburg
47. Clinical relevance of FTO rs9939609 as a determinant of cardio-metabolic risk in South African patients with major depressive disorder
H K Luckhoff, M J Kotze
48. Childhood abuse and neglect as predictors of deficits in verbal auditory memory in non-clinical adolescents with low anxiety proneness
L Martin, K Martin, S Seedat
49. The changes of pro-inflammatory cytokines in a prenatally stressed febrile seizure animal model and whether Rhus chirindensis may attenuate these changes
A Mohamed, M V Mabandla, L Qulu
50. Influence of TMPRSS6 A736v and HFE C282y on serum iron parameters and age of onset in patients with multiple sclerosis
K E Moremi, M J Kotze, H K Luckhoff, L R Fisher, M Kidd, R van Toorn, S Janse van Rensburg
51. Polypharmacy in pregnant women with serious mental illness
E Thomas, E du Toit, L Koen, D Niehaus
52. Infant attachment and maternal depression as predictors of neurodevelopmental and behavioural outcomes at follow-up
J Nothling, B Laughton, S Seedat
53. Differences in abuse, neglect and exposure to community violence in adolescents with and without PTSD
J Nothling, S Suliman, L Martin, C Simmons, S Seedat
54. Assessment of oxidative stress markers in children with autistic spectrum disorders in Lagos, Nigeria
Y Oshodi, O Ojewunmi, T A Oshodi, T Ijarogbe, O F Aina, J Okpuzor, O C F E A Lesi
55. Change in diagnosis and management of 'gender identity disorder' in pre-adolescent children
S Pickstone-Taylor
56. Brain network connectivity in women exposed to intimate partner violence
A Roos, J-P Fouche, B Vythilingum, D J Stein
57. Prolonged exposure treatment for PTSD in a Third-World, task-shifting, community-based environment
J Rossouw, E Yadin, I Mbanga, T Jacobs, W Rossouw, D Alexander, S Seedat
58. Contrasting effects of early0life stress on mitochondrial energy-related proteins in striatum and hippocampus of a rat model of attention-deficit/ hyperactivity disorder
V Russell, J Dimatelis, J Womersley, T-L Sterley
59. Attention-deficit hyperactivity disorder in adults: A South African perspective
R Schoeman, M de Klerk, M Kidd
60. Cognitive function in women with HIV infection and early-life stress
G Spies, C Fennema-Notestine, M Cherner, S Seedat
61. Changes in functional connectivity networks in bipolar disorder patients after mindfulness-based cognitic therapy
J A Starke, C F Beckmann, N Horn
62. Post-traumatic stress disorder, overweight and obesity: A systematic review and meta-analysis
S Suliman, L Anthonissen, J Carr, S du Plessis, R Emsley, S M J Hemmings, C Lochner, N McGregor L van den Heuvel, S Seedat
63. The brain and behaviour in a third-trimester equivalent animal model of fetal alcohol spectrum disorders
P C Swart, C B Currin, J J Dimatelis, V A Russell
64. Irritability Assessment Model (IAM) to monitor irritability in child and adolescent psychiatric disorders.
D van der Westhuizen
65. Outcome of parent-adolescent training in chilhood victimisation: Adaptive functioning, psychosocial and physiological variables
D van der Westhuizen
66. The effect of ketamine in the Wistar-Kyoto and Sprague Dawley rat models of depression
P J van Zyl, J J Dimatelis, V A Russell
67. Investigating COMT variants in anxiety sensitivity in South African adolescents
L J Zass, L Martin, S Seedat, S M J Hemmings
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